Makeblock Orion boards will not work on the latest OSX. Installing drivers from sources such as https://medium.com/@tony92151/arduino-ch340-chip-driver-for-high-sierra-39e621dae1e4 will also fail. The same problem exist for all CH340/CH341 based board such as NodeMCU.
Makeblock must contact http://wch.cn to ask them to update their drivers to support Kernel Extensions since the current will not work.